You can position the spindle either prior to starting production of a new job (machine at zero speed, printed web released) or during production.
 

Operating steps for a new job:

Select the desired machine component (except the key colour print unit).
Touch this area to move the spindle
to its centred position (start position
for the largest spindle adjustment possible in both directions).
Repeat steps 1and 2 until all spindles are positioned on their centred position.